Transplantation of Ex vivo Expanded Cord Blood

 

Elizabeth J. Shpall, Simon Robinson, Marcos de Lima, Krishna Komanduri, John D. McMannis, Laurence Cooper, Laura Worth, Chitra Hosing, Ian K. McNiece and Richard E. Champlin

 

Biology of Blood and Marrow Transplantation
Volume 13, Issue 11, November 2007, Page 1396

 

Cord blood (CB) is rapidly becoming an important source of hematopoietic stem and progenitor cells (HSPC) for transplant for cancer patients. Advantages associated with the use of CB include the ready availability, increased ethnic diversity of the tissue (ethnic minorities are poorly represented in current blood and bone marrow registries) and a reduced risk of graft-versus-host disease (GvHD) at transplant.